High potassium: what it means and what to do
A high potassium result is often false: during the draw, potassium can leak out of cells into the tube. That is why a first high result is usually repeated. If it is real, kidneys that filter less or blood pressure medicines are often behind it. Above 5.5 it needs a doctor today.
What high potassium means
Potassium sits almost entirely inside your cells. If too much leaks out, or your kidneys cannot clear it, the level in your blood rises.
The first step is to check whether it is real: a repeat test is often normal. If it stays high, your doctor looks for the cause, usually the kidneys or medicines.
What causes high potassium
The first is the most common, and it does not mean a disease.
- The draw itself: A clenched fist, a difficult vein or a shaken tube let potassium out of cells. It only rises in the tube.
- Kidneys that filter less: Your kidneys clear the extra potassium. If they filter less, it builds up: eGFR shows it.
- Blood pressure and heart medicines: ACE inhibitors, ARBs (sartans) and spironolactone, for example, make your body hold on to potassium. Do not stop them on your own: talk to your doctor.
- Anti-inflammatories: Medicines such as ibuprofen, taken often, can raise it, especially if your kidneys filter less.
- Salt substitutes and supplements: Salt substitutes contain potassium and, with potassium supplements, can raise the number. Tell your doctor.
- Adrenal glands: If they make too few hormones, potassium rises and sodium often falls. This is rare.
Symptoms
Often none, even when it is high. That is why it is almost always found on a blood test.
When it is very high there can be muscle weakness, tingling, nausea, palpitations or an irregular heartbeat.
With a high potassium, palpitations, very weak muscles or fainting are an emergency: call 112 or go to the emergency department.
False high potassium: when the draw is to blame
This happens often. If you clench your fist or the vein is hard to find, potassium leaks out of cells. The same happens if the tube is shaken, stored badly or analysed many hours later. The number rises in the tube, not in your body.
Sometimes the report flags it, with a note such as haemolysed sample. Very high platelets or white cells can also raise potassium in the tube.
A new draw, with your hand relaxed, usually settles it. But you cannot assume it is false: above 5.5 see a doctor today, and above 6 go to the emergency department.
Which tests to read alongside it
These tests help show whether the number is real and where it comes from.
What your result means
The upper end of the scale, in mmol/L.
- Within your report’s limits, Usually 3.5 to 5.1: Normal. Your heart and muscles have the potassium they need. In the Rosa report you also see whether you are in your optimal range.
- Above your report’s limit, Usually above 5.1, up to 5.5: High. It is often an effect of the draw. Sometimes the kidneys or a medicine are behind it. Talk to your doctor, who usually asks for a repeat draw soon.
- Above 5.5, up to 6: Very high. It can still be the draw, but if it is real it can upset your heart rhythm. See your doctor today, or the out-of-hours doctor if you cannot reach them: the test is usually repeated straight away. With palpitations, very weak muscles or fainting, call 112 or go to the emergency department.
- Above 6: Extremely high. It is often the draw, but if it is real the heart is at risk of dangerous irregular beats. Go to the emergency department today for a repeat test and an ECG, even if you feel well. With palpitations, very weak muscles or fainting, call 112 or go to the emergency department.
What to do if your potassium is high
First find out whether it is real, then remove the cause, with your doctor. Where to start:
- Above 5.5, see a doctor today, even if you feel fine. Above 6, go to the emergency department today.
- Just above the limit, talk to your doctor: they usually ask for a repeat draw soon.
- At the repeat draw, keep your hand relaxed and do not clench your fist.
- Do not stop blood pressure or heart medicines on your own: if they need changing, your doctor decides.
- If you use a salt substitute or take potassium supplements, tell your doctor.
- Before taking anti-inflammatories such as ibuprofen, ask your doctor.
- What to eat: change your diet only if your doctor tells you to. If your kidneys filter less, you may be asked to limit some potassium-rich foods.
When to worry
Talk to a doctor if:
- Your potassium is above your report’s limit, even slightly.
- It is above 5.5: see your doctor today, or the out-of-hours doctor if you cannot reach them.
- It is above 6: go to the emergency department today, for a repeat test and an ECG.
- It stays high on the repeat draw.
- It is high and your kidneys filter less, or you take blood pressure medicines.
- Your potassium is out of range and you have palpitations, very weak muscles or fainting: call 112 or go to the emergency department.
With Rosa, a potassium above 5.5 mmol/L is always flagged to a doctor, urgently.
Frequently asked questions
High potassium: when should I worry? Just above the limit, talk to your doctor: the repeat test is often normal. Above 5.5 see a doctor today, even if you feel fine, and above 6 go to the emergency department. With palpitations, very weak muscles or fainting, call 112 or go to the emergency department.
Slightly high potassium: can it be an error? Yes, it happens often: potassium can leak out of cells during the draw. That is why your doctor usually repeats it, and looks for a cause if it stays high.
What are the symptoms of high potassium? Often none. When it is very high there can be weakness, tingling, nausea or palpitations. With palpitations, very weak muscles or fainting, call 112 or go to the emergency department.
High potassium: what should I avoid eating? If your kidneys are fine, you usually do not need to change your diet: the cause matters. If they filter less, your doctor may ask you to limit some potassium-rich foods, such as nuts, legumes and potatoes, and salt substitutes.
Is high potassium dangerous? If it is real and very high, yes: it can make your heartbeat irregular. That is why above 5.5 it should be seen today, and above 6 at the emergency department, even though the repeat test is often normal.
I take blood pressure medicines: is that why my potassium is high? It may be: some, such as ACE inhibitors, sartans and spironolactone, hold on to potassium. That is why your doctor checks it. Do not stop them on your own: bring your doctor the report.
Sources
- Clase and colleagues, potassium balance and how to manage high and low levels: conclusions of a KDIGO Controversies Conference. Kidney International, 2020. PMID 31706619
- KDIGO clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney International, 2024. PMID 38490803
- Don and colleagues, falsely high potassium caused by fist clenching during the blood draw. New England Journal of Medicine, 1990. PMID 2325722
- Huang and Kuo, why magnesium deficiency makes you lose potassium. Journal of the American Society of Nephrology, 2007. PMID 17804670
- Penninkilampi and colleagues, regular liquorice raises blood pressure and lowers potassium: a systematic review and meta-analysis. Journal of Human Hypertension, 2017. PMID 28660884