Blood potassium: what it is, what it tells you and why we test it
Potassium is a mineral that sits almost entirely inside your cells. Only a little circulates in your blood, and your body holds it within very narrow limits, because it runs your heartbeat and your muscles. A surprise high result is often an effect of the blood draw itself.
Why we test it
Potassium keeps your nerves and muscles working, heart included. That is why your body holds it in a narrow window, and your kidneys clear the extra.
Both too much and too little can upset your heart rhythm. And because the range is narrow, even a value slightly out of range matters.
Common medicines often shift it, such as blood pressure pills and diuretics, and so do kidneys that filter less. It usually causes no symptoms until it is well out of range.
What it tells you, and what it does not
If it is high, the draw is often the reason: red cells break in the tube and release potassium. That is why a first high result is usually repeated.
If it stays high on the repeat test, the kidneys or some medicines are usually involved. If it is low, diuretics, vomiting or diarrhoea are often behind it.
It does not tell you how much potassium you eat: with healthy kidneys, food moves it very little.
That is why it is read together with other tests:
- Creatinine: Shows whether your kidneys work well
- eGFR: How well your kidneys filter: if they filter less, potassium rises
- Sodium: If it is out of range too, fluid loss or medicines are often behind it
- Magnesium: If it is short, potassium struggles to come back up
Normal potassium levels
The lab decides what is normal. It is usually 3.5 to 5.1 mmol/L, the same for women and men. Your own report may print different limits.
Some reports print mEq/L instead of mmol/L: for potassium the number is the same. You may also see it written as K.
How the draw went matters a lot: a damaged sample can make it look higher than it is.
In the Rosa report you also see your optimal range, next to creatinine and eGFR.
What your result means
Find the row for your result, in mmol/L. Which values are dangerous? Below 3.5 should always be seen by a doctor, below 3 or above 5.5 today, and above 6 at the emergency department.
- Below 3: Very low. It can cause weakness, cramps and an irregular heartbeat. See your doctor today, or the out-of-hours doctor if you cannot reach them. With palpitations, very weak muscles or fainting, call 112 or go to the emergency department.
- 3 to under 3.5: Low. Diuretics, vomiting or diarrhoea are often behind it. Talk to your doctor soon and do not take potassium supplements on your own. With palpitations, very weak muscles or fainting, call 112 or go to the emergency department.
- Within your report’s limits, Usually 3.5 to 5.1: Normal. Your heart and muscles have the potassium they need. In the Rosa report you also see whether you are in your optimal range.
- Above your report’s limit, Usually above 5.1, up to 5.5: High. It is often an effect of the draw. Sometimes the kidneys or a medicine are behind it. Talk to your doctor, who usually asks for a repeat draw soon.
- Above 5.5, up to 6: Very high. It can still be the draw, but if it is real it can upset your heart rhythm. See your doctor today, or the out-of-hours doctor if you cannot reach them: the test is usually repeated straight away. With palpitations, very weak muscles or fainting, call 112 or go to the emergency department.
- Above 6: Extremely high. It is often the draw, but if it is real the heart is at risk of dangerous irregular beats. Go to the emergency department today for a repeat test and an ECG, even if you feel well. With palpitations, very weak muscles or fainting, call 112 or go to the emergency department.
If your potassium is high or low
- High potassium: It is often an effect of the draw. If it is real, the kidneys or medicines are usually behind it.
- Low potassium: Diuretics, vomiting or diarrhoea are often behind it. It can cause cramps and palpitations.
What can skew the result
Potassium is very sensitive to how the draw goes. It helps to know this before you read it.
- A clenched fist: Opening and closing your hand during the draw lets potassium out of your muscles. Keep your hand relaxed.
- A difficult draw: If the vein is hard to find or the tourniquet stays tight for long, the number can rise.
- A shaken or waiting tube: If the tube is shaken, stored badly or analysed many hours later, red cells release potassium. Sometimes the report flags it.
- Salt substitutes or supplements: Salt substitutes contain potassium and, like supplements, can raise the number. Tell your doctor.
When to worry
Talk to a doctor if:
- Your potassium is below 3.5.
- It is below 3 or above 5.5: see your doctor today, or the out-of-hours doctor if you cannot reach them. Above 6, go to the emergency department today.
- It is above your report’s limit, even slightly: your doctor usually asks for a repeat draw soon.
- It is out of range and you take blood pressure or heart medicines, diuretics or supplements.
- Your potassium is out of range and you have palpitations, very weak muscles or fainting: call 112 or go to the emergency department.
With Rosa, a potassium below 3.5 mmol/L is always flagged to a doctor, and below 3 or above 5.5 urgently.
Frequently asked questions
What does K mean on my report? It is the chemical symbol for potassium. Italian reports may also call it potassiemia or kaliemia: all names for the potassium in your blood.
Do I need to fast for a potassium test? Not for potassium. It is usually done with other tests that do need fasting, though, so it is best to arrive fasted. During the draw, keep your hand relaxed.
Does blood potassium show how much potassium I eat? Hardly. With healthy kidneys your body clears the extra, and the level stays steady. Medicines, the kidneys or fluid loss move it more often.
Why are potassium and magnesium read together? Because when magnesium is short, your kidneys lose more potassium and the level struggles to come back up. So with a low potassium, doctors check magnesium too.
How often should it be checked? For people who feel well there is no fixed rule: Rosa measures it once a year. People on some blood pressure medicines or diuretics have it checked more often, on their doctor’s schedule.
Sources
- Clase and colleagues, potassium balance and how to manage high and low levels: conclusions of a KDIGO Controversies Conference. Kidney International, 2020. PMID 31706619
- KDIGO clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney International, 2024. PMID 38490803
- Don and colleagues, falsely high potassium caused by fist clenching during the blood draw. New England Journal of Medicine, 1990. PMID 2325722
- Huang and Kuo, why magnesium deficiency makes you lose potassium. Journal of the American Society of Nephrology, 2007. PMID 17804670
- Penninkilampi and colleagues, regular liquorice raises blood pressure and lowers potassium: a systematic review and meta-analysis. Journal of Human Hypertension, 2017. PMID 28660884