Vitamin K: what it is, what it tells you and when it’s tested
Your liver needs vitamin K to make the proteins that let your blood clot. It also plays a part in your bones. It comes in two forms: K1, in leafy greens, and K2, in fermented foods and some cheeses.
When it’s tested
It is rarely measured. Doctors order it when they suspect a shortage: with bleeding or bruising for no reason, with conditions that absorb fat poorly, such as coeliac disease, cystic fibrosis or bile duct disease, or in people who eat very little and take antibiotics for a long time.
Usually the doctor looks first at clotting tests such as the INR. These are read in context, often in hospital. If you have bleeding that will not stop, call 112 or go to the emergency department.
It is not a test for people who feel well: in healthy adults a shortage is rare, and the value depends mostly on what you ate in the days before. That is why Rosa does not test it, and it does not run clotting tests either. It does measure platelets, haemoglobin and your liver, which makes the clotting proteins.
What it tells you, and what it does not
It shows how much vitamin K1 is in your blood right now. It mostly reflects your recent meals, and it does not measure K2.
To see whether your liver has enough to do its work, some labs measure a protein called PIVKA-II, which rises when vitamin K is short. The INR, by contrast, only rises with a marked shortage.
That is why it is read together with other tests:
- INR: It rises when vitamin K is very short, or with warfarin
- aPTT: Another clotting test
- Platelets: If you bleed easily, your doctor looks at them too
- ALT and AST: Your liver uses vitamin K to make the clotting proteins
Normal vitamin K levels
There is no single range. Few labs run this test, and different methods give different numbers. The range printed next to your result is what counts.
As a guide, experts consider a vitamin K1 value below 0.15 µg/L a shortage.
Fasting matters: a meal with leafy greens can raise the value for a few hours.
If your vitamin K is low or high
- Low vitamin K: It can come from a poor meal or a real shortage. Your doctor looks at your symptoms and clotting tests.
- High vitamin K: It usually reflects a meal rich in greens or a supplement. No harm is known from vitamin K in food.
Who is at risk of a vitamin K shortage
In healthy adults it is rare. It is more common in these cases:
- A bowel that absorbs fat poorly: Coeliac disease, cystic fibrosis, pancreas or bile duct disease.
- Antibiotics and poor meals: A long course of antibiotics in someone who eats very little, for example during a hospital stay.
- Malnutrition: Very poor diets, older people who eat little, serious kidney disease or cancer.
- Newborn babies: They are born with small stores. That is why every newborn is given vitamin K at birth.
Symptoms of a shortage
A shortage shows mainly through bleeding:
- Bruising easily
- Nosebleeds or bleeding gums
- Heavier periods than usual
- Cuts that bleed for a long time
If you have blood in your urine or black stools, vomit blood or have bleeding that will not stop, call 112 or go to the emergency department.
Vitamin K and blood thinners
Warfarin and acenocoumarol work by blocking vitamin K. That is why how much vitamin K you eat can change their effect and your INR.
You do not need to cut out green vegetables. What matters is eating similar amounts week after week, without big sudden changes. If you change your diet a lot, tell your doctor.
Before starting or stopping a supplement that contains vitamin K, K2 included, talk to your doctor. Never change the dose of your blood thinner on your own: your doctor sets the INR you should reach. If you take another kind of blood thinner, ask your doctor whether diet matters for you too.
Where it is found: what to eat
Vitamin K is found mostly in vegetables. For example:
- Leafy greens: spinach, chard, lettuce, rocket
- Cabbages: broccoli, cavolo nero, Brussels sprouts, turnip tops
- Parsley and other fresh herbs
- Vegetable oils, such as olive oil
- For K2: aged cheese, egg yolk and fermented foods
A diet with vegetables every day is usually enough. Ask your doctor before taking supplements, especially if you take blood thinners.
What can skew the result
A few things change the value without changing your stores.
- A meal: Vegetables eaten recently raise the value. That is why the test is done fasting.
- Supplements: Even a multivitamin can contain it. Say so before the blood draw.
- Blood fats: Vitamin K travels with fats: high triglycerides can raise it.
- The lab: Few labs measure it, with different methods. Always compare with the range on your report.
When to worry
Talk to your doctor if:
- You bruise easily, or often have nosebleeds or bleeding gums.
- You have a condition that absorbs fat poorly and notice these signs.
- You take warfarin or acenocoumarol and want to change your diet or start a supplement.
- Your INR is outside the range your doctor gave you.
- You have blood in your urine or black stools, vomit blood, get a sudden severe headache or have bleeding that will not stop: call 112 or go to the emergency department.
Frequently asked questions
What does vitamin K do? Your liver needs it to make the proteins that let your blood clot. It also plays a part in your bones.
Which foods contain vitamin K? Mostly leafy greens and cabbages: spinach, chard, lettuce, rocket, broccoli, cavolo nero, turnip tops. K2 is in aged cheese, egg yolk and fermented foods.
Can I eat green vegetables if I take warfarin? Yes. You do not need to cut them out: what matters is eating similar amounts each week. If you change your diet a lot, tell your doctor, who can check your INR. Never change the dose on your own.
Is vitamin K2 good for bones and arteries? Its role is being studied, but the evidence is not enough to recommend it to healthy people. If you take blood thinners, do not start it without talking to your doctor.
Why are newborns given vitamin K? Newborns are born with small stores, and breast milk contains little. A dose at birth prevents rare but serious bleeding.
Does Rosa test vitamin K? No, and it does not run INR or aPTT either. Rosa measures platelets, haemoglobin and ALT and AST. If your doctor wants vitamin K or clotting tests, they order them separately.
Sources
- Card, Gorska and Harrington, laboratory assessment of vitamin K status. Journal of Clinical Pathology, 2020. PMID 31862867
- Violi and colleagues, interaction between dietary vitamin K intake and anticoagulation by vitamin K antagonists: a systematic review. Medicine, 2016. PMID 26962786
- Shearer, vitamin K deficiency bleeding (VKDB) in early infancy. Blood Reviews, 2009. PMID 18804903
- EFSA Panel on Dietetic Products, Nutrition and Allergies, dietary reference values for vitamin K. EFSA Journal, 2017. PMID 32625486