Low albumin: causes, symptoms and what to do
A low albumin usually does not mean you eat too little protein. More often inflammation or an illness is behind it, and CRP helps tell. More rarely the liver makes less of it, or the kidneys and gut lose it.
What low albumin means
Your liver makes albumin. It drops when your body loses or uses up more of it, or when the liver makes less.
The most common reason is inflammation. During an illness, albumin leaks out of the blood vessels and lasts less long, even though the liver makes more. That is why it is read with CRP.
It also depends on the lab: many reports use wider limits, and often g/L instead of g/dL. Check your own report’s limit first.
What causes low albumin
The first is the most common.
- Inflammation or illness: An infection, a flu or a long-term illness makes it drop. CRP is usually high too.
- Pregnancy: The blood gets more diluted and the number drops. That is normal.
- Eating too little: This matters mostly in older people or after a long illness. With a normal diet, it is usually not the cause.
- A liver that makes less: This happens with advanced liver disease, which is rarer. Other liver tests are usually abnormal too.
- Kidneys that lose it: If your kidneys let protein through, albumin ends up in your urine. The urine albumin test shows it.
- A gut that loses it: Some gut diseases make you lose it, or absorb food poorly. They are rarer.
Symptoms
If it is only slightly low, usually none. You more often feel the symptoms of the cause, such as fever or tiredness during an illness.
When it is very low, water leaks out of the blood vessels and collects in the tissues. You may notice:
- Swollen legs and ankles
- Puffiness around the eyes, especially in the morning
- Tiredness and weakness
Very foamy urine can mean protein in the urine: talk to your doctor. These symptoms can have other causes too.
Low albumin in older people
Albumin drops a little with age, even in healthy people. But in older people a low number deserves attention: it often signals an illness, inflammation or eating too little.
It goes along with losing muscle and strength, which is why it matters. Enough protein and moving every day help the muscles, even if they do not always bring albumin back up.
If an older relative has low albumin, take the report to their doctor: the cause is usually looked for first, then the diet.
Which tests to read alongside it
These tests help find the cause.
What your result means
The lower end of the scale, in g/dL. If your report uses g/L, divide by ten.
- Below your report’s limit, On some reports below 4.02: Low. Inflammation or an illness is usually behind it, more rarely the liver, the kidneys or diet. If your report marks it as normal, it is usually fine. Otherwise read it with your CRP and show it to your doctor.
- Within your report’s limits, On some reports 4.02 to 4.76: Normal. Usually fine. It is a stable number, so how it changes from year to year counts too. In the Rosa report you also see whether you are in your optimal range.
What to do and what to eat
First the cause is looked for: while it lasts, albumin stays low. Where to start:
- Check CRP, urine albumin and the liver tests on your report.
- Show your report to your doctor, who decides whether to repeat the test or do others.
- If you have recently had a flu or an infection, say so: it often explains the drop.
- What to eat: have some protein at every meal, for example fish, eggs, yoghurt, legumes, poultry or fresh cheese.
- Protein matters most for people who eat little and for older people, together with exercise. If inflammation is the cause, protein alone does not bring albumin back up.
- With kidney or liver disease, your doctor decides how much protein to eat.
When to worry
Talk to your doctor if:
- It is low for your report and you do not know why.
- It is low together with a high CRP, a high bilirubin or albumin in your urine.
- You have swelling in your legs, ankles or around your eyes.
- Your urine is very foamy.
- You are losing weight without trying, or eating very little.
- Your eyes or skin are yellow, or you have dark urine or pale stools: see a doctor today. If you also have a fever or bad pain in your belly, call 112 or go to the emergency department.
- One leg is swollen and painful, or you are suddenly short of breath: call 112 or go to the emergency department.
Frequently asked questions
Does low albumin mean I eat too little protein? Usually not, and it is the most common mistake. More often inflammation is behind it, and that lowers it whatever you eat: CRP helps tell. Eating too little matters mostly in older people or after a long illness.
Is low albumin serious? Usually not, if it is only a little below the limit and you feel well: a passing illness is often behind it. What matters is the cause, to find with your doctor, especially if you have swelling or are older.
How long does albumin take to come back up? Weeks, not days: albumin changes slowly. Once the cause is gone, for example inflammation, it usually comes back up within a few weeks.
Can low albumin make your legs swell? Yes, when it is very low: water leaks out of the blood vessels and collects in the tissues, above all in the legs and ankles. But swollen legs often have other causes: talk to your doctor.
Low albumin in pregnancy: is it normal? Usually yes: in pregnancy the blood gets more diluted and the number drops. If your face or hands swell suddenly, contact your obstetrician the same day. With a severe headache, blurred vision or pain in your upper belly, call 112 or go to the emergency department.
Sources
- Newsome and colleagues, guidelines on the management of abnormal liver blood tests. Gut, 2018. PMID 29122851
- Soeters and colleagues, low albumin: why it happens and what it means. Journal of Parenteral and Enteral Nutrition, 2019. PMID 30288759
- Lippi and colleagues, how a tourniquet left on for one or three minutes changes blood test results. Clinical Chemistry and Laboratory Medicine, 2005. PMID 16201899
- Lippi and colleagues, lying, sitting or standing before a blood draw changes many test results. Clinica Chimica Acta, 2015. PMID 25437911
- Bruun-Rasmussen and colleagues, reference intervals for twelve common blood tests in healthy Danish adults. Scandinavian Journal of Clinical and Laboratory Investigation, 2021. PMID 33426932